Human Integrin Alpha-5 (ITGA5) Protein
546€ (100 µg)
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name
Human Integrin Alpha-5 (ITGA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620292
tested applications
ELISA, WB, SDS-PAGE
Description
Human Integrin Alpha-5 (ITGA5) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Integrin Alpha-5 (ITGA5) |
| Host | Mammalian cells |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 109.57 kDa Sequence Fragment: Met1-Tyr995 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08648 |
| Alias | FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F |
| Background | Protein ITGA5 |
| Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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ITGA5 antibody
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
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