Human Integrin Alpha 5 (ITGa5) Protein

Human Integrin Alpha 5 (ITGa5) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ITGa5

proveedor

Abbexa

reference

abx067272

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Integrin Alpha 5 (ITGa5) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

Integrin subunit alpha 5 (ITGA5) is a critical component of the integrin family of transmembrane receptors, responsible for mediating interactions between cells and the extracellular matrix (ECM). ITGA5 pairs with integrin subunit beta 1 (ITGB1) to form the α5β1 integrin, also known as the fibronectin receptor. This integrin complex plays an essential role in cell adhesion, migration, proliferation, and survival by binding to fibronectin, an ECM glycoprotein. ITGA5-mediated interactions are important for various physiological processes, including embryonic development, wound healing, angiogenesis, and the regulation of cell differentiation. Dysregulation of ITGA5 has been implicated in several pathologies, such as fibrosis, cancer, and inflammatory diseases.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Integrin Alpha 5 (ITGa5)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 47.6 kDa Observed MW (SDS-PAGE): 48 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu895-Ala1049 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ITGa5


dry ice

No


availability

Shipped within 5-7 working days.


alias

FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reactivity

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clonality

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