Human Integrin Alpha 5 (ITGa5) Protein

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221€ (10 µg)

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935106861
info@markelab.com
name
Human Integrin Alpha 5 (ITGa5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067272
tested applications
WB, SDS-PAGE

Description

Human Integrin Alpha 5 (ITGa5) is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Integrin Alpha 5 (ITGa5)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Glu895-Ala1049
Tag: N-terminal His tag and GST tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 47.6 kDa  Observed MW (SDS-PAGE): 48 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P08648
Alias
FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F
Background
Protein ITGa5
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Integrin subunit alpha 5 (ITGA5) is a critical component of the integrin family of transmembrane receptors, responsible for mediating interactions between cells and the extracellular matrix (ECM). ITGA5 pairs with integrin subunit beta 1 (ITGB1) to form the α5β1 integrin, also known as the fibronectin receptor. This integrin complex plays an essential role in cell adhesion, migration, proliferation, and survival by binding to fibronectin, an ECM glycoprotein. ITGA5-mediated interactions are important for various physiological processes, including embryonic development, wound healing, angiogenesis, and the regulation of cell differentiation. Dysregulation of ITGA5 has been implicated in several pathologies, such as fibrosis, cancer, and inflammatory diseases.

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