Human Insulin Like Growth Factor Binding Protein 7 (IGFBP7) CLIA Kit
643.5€ (96 tests)
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name
Human Insulin Like Growth Factor Binding Protein 7 (IGFBP7) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195066
tested applications
CLIA
Description
Human Insulin Like Growth Factor Binding Protein 7 (IGFBP-7) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Insulin Like Growth Factor Binding Protein 7 (IGFBP-7).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Insulin Like Growth Factor Binding Protein 7 (IGFBP7) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | 0.1 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1,IGF-binding protein 7 |
| Background | CLIA Kits IGFBP7 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
IGFBP7 is a member of the insulin-like growth factor binding protein family that regulates the availability and activity of insulin-like growth factors (IGFs) by binding to them with high affinity Unlike other IGFBPs, IGFBP7 also binds to insulin, modulating its signaling and promoting metabolic homeostasis IGFBP7 plays a critical role in regulating cell growth, apoptosis, and senescence and has anti-tumorigenic properties by inhibiting the mitogenic effects of IGFs Its expression is downregulated in cancers such as colorectal, breast, and prostate cancer where it acts as a tumor suppressor IGFBP7 also plays roles in cardiovascular health by influencing vascular smooth muscle cell proliferation and in fibrosis by mediating tissue remodeling and extracellular matrix deposition
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