Human INSIG1 (Insulin-induced gene 1 protein) ELISA Kit
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name
Human INSIG1 (Insulin-induced gene 1 protein) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH9421
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 31.25-2000pg/ml |
| Sensitivity | 18.75pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | O15503 |
| Alias | Insulin-induced gene 1 protein, INSIG-1, INSIG1 |
| Background | Elisa kits for INSIG1 |
| Status | RUO |
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Human INSIG1 (Insulin-induced gene 1 protein) ELISA Kit
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INSIG1 antibody
Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation(ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
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