Human Immunoglobulin Superfamily, Member 2 (IGSF2) Protein

Este producto es parte de IGSF - immunoglobulin superfamily member
Product Graph
221€ (10 µg)

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935106861
info@markelab.com
name
Human Immunoglobulin Superfamily, Member 2 (IGSF2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166678
tested applications
WB, SDS-PAGE

Description

Immunoglobulin Superfamily, Member 2 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Immunoglobulin Superfamily, Member 2 (IGSF2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 28.8 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Ala566-Leu784
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q93033
Alias
V7,IGSF2,EWI-101,Glu-Trp-Ile EWI motif-containing protein 101,Cell surface glycoprotein V7
Background
Protein IGSF2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

IGSF2, also known as CD101, is a glycoprotein expressed on immune cells, including T cells, dendritic cells, and monocytes. It plays a role in regulating immune responses, particularly in modulating T cell activation and promoting immune tolerance. Structurally, IGSF2 contains multiple Ig-like domains, which enable interactions with other immune cell receptors and ligands. IGSF2 has been implicated in inflammatory diseases such as inflammatory bowel disease (IBD), where its dysregulation may contribute to immune hyperactivation. It is also being studied for its role in tumor immunity and autoimmune disease susceptibility.

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