Human Hydroperoxide Isomerase ALOXE3 (ALOXE3) ELISA Kit

Este producto es parte de ALOX - Arachidonate lipoxygenase
Human Hydroperoxide Isomerase ALOXE3 (ALOXE3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

587.5€ (96 tests)

Elisa Kits ALOXE3

proveedor

Abbexa

reference

abx572541

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Hydroperoxide Isomerase ALOXE3 (ALOXE3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Hydroperoxide Isomerase ALOXE3 (ALOXE3) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ALOXE3 is a member of the lipoxygenase family that functions as an epidermal lipoxygenase critical for skin barrier formation and maintenance. Unlike other lipoxygenases, ALOXE3 acts as a hydroperoxide isomerase, converting epoxyalcohol intermediates into key lipid mediators required for the assembly of the cornified lipid envelope in the epidermis. ALOXE3 is specifically expressed in the skin and is essential for proper lipid metabolism during keratinocyte differentiation. Mutations in the ALOXE3 gene are linked to autosomal recessive congenital ichthyosis (ARCI), a disorder characterized by dry, scaly skin due to defective epidermal lipid processing and barrier dysfunction. In addition to its role in skin biology, ALOXE3 may contribute to anti-inflammatory pathways by regulating lipid signaling in epithelial tissues. Emerging research suggests that ALOXE3 dysfunction may influence wound healing, oxidative stress responses, and epithelial tissue repair. Its unique enzymatic activity makes it essential for skin homeostasis and a potential therapeutic target for treating barrier-related skin diseases.

Características del producto

category

ELISA Kits


immunogen target

Hydroperoxide Isomerase ALOXE3 (ALOXE3)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

Epidermis-type lipoxygenase 3


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ALOXE3


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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