Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
689€ (96 tests)
Elisa kits for CD74
proveedor
Abbexareference
abx352233Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) concentrations in serum, plasma, tissue homogenates and other biological fluids.
Background
CD74, also known as the invariant chain (Ii), is a type II transmembrane glycoprotein that plays a critical role in the immune system, particularly in antigen processing and presentation. CD74 is encoded by the CD74 gene and is primarily expressed on antigen-presenting cells (APCs) such as B cells, dendritic cells, and macrophages, although it is also found on some non-immune cells, including certain epithelial and cancer cells. One of its central functions is to act as a chaperone for major histocompatibility complex class II (MHC-II) molecules, ensuring the proper folding, trafficking, and peptide loading of MHC-II, which is essential for the presentation of antigens to CD4+ T cells. In addition to its role in antigen presentation, CD74 also functions as a receptor for macrophage migration inhibitory factor (MIF), which modulates inflammatory responses and cell survival pathways.
Características del producto
category
ELISA Kits
immunogen target
HLA Class II Histocompatibility Antigen Gamma Chain (CD74)
reactivity
Human
test range
46.9 pg/ml - 3000 pg/ml
sensitivity
< 18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
p33,CLIP,DHLAG,HLADG,Ia-GAMMA,HLA class II histocompatibility antigen gamma chain,HLA-DR antigens-associated invariant chain,Ia antigen-associated invariant chain (Ii)
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD74
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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