Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) ELISA Kit

Este producto es parte de CD74 - CD74 molecule
Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

689€ (96 tests)

Elisa kits for CD74

proveedor

Abbexa

reference

abx352233

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human HLA Class II Histocompatibility Antigen Gamma Chain (CD74) concentrations in serum, plasma, tissue homogenates and other biological fluids.


Background

CD74, also known as the invariant chain (Ii), is a type II transmembrane glycoprotein that plays a critical role in the immune system, particularly in antigen processing and presentation. CD74 is encoded by the CD74 gene and is primarily expressed on antigen-presenting cells (APCs) such as B cells, dendritic cells, and macrophages, although it is also found on some non-immune cells, including certain epithelial and cancer cells. One of its central functions is to act as a chaperone for major histocompatibility complex class II (MHC-II) molecules, ensuring the proper folding, trafficking, and peptide loading of MHC-II, which is essential for the presentation of antigens to CD4+ T cells. In addition to its role in antigen presentation, CD74 also functions as a receptor for macrophage migration inhibitory factor (MIF), which modulates inflammatory responses and cell survival pathways.

Características del producto

category

ELISA Kits


immunogen target

HLA Class II Histocompatibility Antigen Gamma Chain (CD74)


reactivity

Human


test range

46.9 pg/ml - 3000 pg/ml


sensitivity

< 18.8 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

p33,CLIP,DHLAG,HLADG,Ia-GAMMA,HLA class II histocompatibility antigen gamma chain,HLA-DR antigens-associated invariant chain,Ia antigen-associated invariant chain (Ii)


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

CD74


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human CD74(HLA class II histocompatibility antigen gamma chain) ELISA Kit

Human CD74(HLA class II histocompatibility antigen gamma chain) ELISA Kit

proveedor

FineTest

reference

EH1531

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse Cd74(HLA class II histocompatibility antigen gamma chain) ELISA Kit

Mouse Cd74(HLA class II histocompatibility antigen gamma chain) ELISA Kit

proveedor

FineTest

reference

EM6405

reactivity

mouse

status

RUO

Precio a consultar

Ver más

anti- CD74 antibody

anti- CD74 antibody

proveedor

FineTest

reference

FNab09829

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

monoclonal

Precio a consultar

Ver más