Human High Mobility Group Protein B1 (HMGB1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
585€ (96 tests)
Elisa kits for HMGB1
proveedor
Abbexareference
abx253840Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human High Mobility Group Protein B1 (HMGB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human HMGB1 concentrations in serum, plasma, tissue homogenates and other biological fluids.
Background
HMGB1 is a non-histone nuclear protein involved in DNA repair, replication, and transcriptional regulation, but it also functions as a damage-associated molecular pattern (DAMP) protein when released extracellularly Upon cellular stress or necrosis, HMGB1 is actively secreted or passively released, triggering immune responses by interacting with receptors such as RAGE and TLR4 HMGB1 is critical in mediating inflammation, immune activation, and tissue injury, playing roles in diseases like sepsis, autoimmune disorders, and cancer It promotes cell migration, angiogenesis, and tumor progression, while dysregulated HMGB1 signaling is linked to chronic inflammation and metastasis Targeting HMGB1 holds therapeutic promise for modulating immune responses in inflammatory diseases, neurodegeneration, and cancer
Características del producto
category
ELISA Kits
immunogen target
High Mobility Group Protein B1 (HMGB1)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
HMG1,HMG3,HMG-1,SBP-1,Amphoterin
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
HMGB1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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