Human Hepatitis B Virus X Interacting Protein (LAMTOR5) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Hepatitis B Virus X Interacting Protein (LAMTOR5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx250764
tested applications
ELISA
Description
Human Hepatitis B Virus X Interacting Protein (LAMTOR5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ragulator complex protein LAMTOR5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Hepatitis B Virus X Interacting Protein (LAMTOR5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O43504 |
| Alias | HBXIP,XIP,Hepatitis B virus X-interacting protein,Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 |
| Background | Elisa kits for LAMTOR5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Ragulator complex protein LAMTOR5 is a critical subunit of the Ragulator complex that anchors Rag GTPases to the lysosomal membrane, facilitating the activation of mTORC1 in response to amino acid and nutrient availability LAMTOR5 stabilizes the Ragulator complex structure and supports mTORC1 signaling, which is essential for regulating cellular metabolism, growth, and autophagy Its role in nutrient sensing and lysosomal positioning makes it vital for cellular homeostasis Studies highlight that loss or dysregulation of LAMTOR5 disrupts mTORC1 activation, leading to impaired protein synthesis, autophagy, and energy balance LAMTOR5 is also involved in immune responses, where mTORC1 signaling regulates T-cell activation and macrophage function Aberrant expression of LAMTOR5 has been linked to metabolic disorders, neurodegenerative diseases, and cancers, where impaired nutrient signaling promotes cellular dysfunction Recent studies suggest its involvement in stress response pathways and lysosomal biogenesis, reinforcing its essential role as a scaffold protein in coordinating lysosome-mTORC1 communication
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