Human Growth Hormone Variant (GH2) Protein
273€ (10 µg)
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Name
Human Growth Hormone Variant (GH2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx260528
Tested Applications
SDS-PAGE
Description
Placental Growth Hormone 20 kDa Protein is a recombinant cytokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Growth Hormone Variant (GH2) |
| Host | E. coli |
| Assay Type | Activity: Not tested |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 98% (SDS-PAGE and SEC-HPLC) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P01242 |
| Alias | GHL,GHV,GH-V,GHB2,hGH-V,Growth hormone variant,Placenta-specific growth hormone |
| Background | Protein GH2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Growth hormone 2 (GH2) is a member of the growth hormone gene family primarily expressed in the placenta, where it plays a critical role in regulating fetal growth and maternal metabolic adaptations during pregnancy GH2 is structurally similar to growth hormone 1 (GH1) but has distinct roles in enhancing placental development and nutrient transport to the fetus It stimulates insulin-like growth factor 1 (IGF-1) production and modulates maternal glucose and lipid metabolism to ensure fetal nutrient supply Dysregulation of GH2 expression has been associated with placental insufficiency, intrauterine growth restriction (IUGR), and gestational diabetes GH2 also influences immune responses during pregnancy, promoting tolerance to the fetus while maintaining maternal immunity Emerging studies suggest that alterations in GH2 expression may contribute to pregnancy complications and metabolic disorders, highlighting its importance in fetal development and maternal physiology
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