Growth Hormone Variant (GH2) Antibody
637€ (100 µl)
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935106861
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name
Growth Hormone Variant (GH2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx112865
tested applications
ELISA, WB
Description
Growth Hormone 2 Antibody is a Rabbit Polyclonal antibody against Growth Hormone 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Growth Hormone Variant (GH2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01242 |
| Gene ID | 2689 |
| NCBI Accession | NP_002050.1, NM_002059.4 |
| OMIM | 139240 |
| Alias | GHL,GHV,GH-V,GHB2,hGH-V,Growth hormone variant,Placenta-specific growth hormone |
| Background | Antibody anti-GH2 |
| Status | RUO |
Descripción
Growth hormone 2 (GH2) is a member of the growth hormone gene family primarily expressed in the placenta, where it plays a critical role in regulating fetal growth and maternal metabolic adaptations during pregnancy GH2 is structurally similar to growth hormone 1 (GH1) but has distinct roles in enhancing placental development and nutrient transport to the fetus It stimulates insulin-like growth factor 1 (IGF-1) production and modulates maternal glucose and lipid metabolism to ensure fetal nutrient supply Dysregulation of GH2 expression has been associated with placental insufficiency, intrauterine growth restriction (IUGR), and gestational diabetes GH2 also influences immune responses during pregnancy, promoting tolerance to the fetus while maintaining maternal immunity Emerging studies suggest that alterations in GH2 expression may contribute to pregnancy complications and metabolic disorders, highlighting its importance in fetal development and maternal physiology
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