Human Growth Hormone Variant (GH2) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Human Growth Hormone Variant (GH2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166821
tested applications
WB, SDS-PAGE
Description
Growth Hormone 2 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Growth Hormone Variant (GH2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe27-Phe217 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | GHL,GHV,GH-V,GHB2,hGH-V,Growth hormone variant,Placenta-specific growth hormone |
| Background | Protein GH2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Growth hormone 2 (GH2) is a member of the growth hormone gene family primarily expressed in the placenta, where it plays a critical role in regulating fetal growth and maternal metabolic adaptations during pregnancy GH2 is structurally similar to growth hormone 1 (GH1) but has distinct roles in enhancing placental development and nutrient transport to the fetus It stimulates insulin-like growth factor 1 (IGF-1) production and modulates maternal glucose and lipid metabolism to ensure fetal nutrient supply Dysregulation of GH2 expression has been associated with placental insufficiency, intrauterine growth restriction (IUGR), and gestational diabetes GH2 also influences immune responses during pregnancy, promoting tolerance to the fetus while maintaining maternal immunity Emerging studies suggest that alterations in GH2 expression may contribute to pregnancy complications and metabolic disorders, highlighting its importance in fetal development and maternal physiology
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