Human GRB2 Associated Binding Protein 3 (GAB3) ELISA Kit

Este producto es parte de GAB - GRB2 associated binding protein
Human GRB2 Associated Binding Protein 3 (GAB3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for GAB3

proveedor

Abbexa

reference

abx387456

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human GRB2 Associated Binding Protein 3 (GAB3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GRB2 Associated Binding Protein 3 concentrations in serum, plasma and other biological fluids.


Background

GAB3 is an adaptor protein structurally related to GAB1 and GAB2, functioning downstream of receptor tyrosine kinases to activate pathways like PI3K/Akt and MAPK/ERK. It is primarily expressed in hematopoietic cells and immune tissues, where it regulates cell survival, proliferation, and differentiation. GAB3 supports B-cell receptor (BCR) and cytokine-mediated signaling, playing a role in B-cell development and macrophage activation. Its dysregulation is associated with altered immune responses and hematopoietic disorders. GAB3 interacts with SH2-containing proteins to modulate signaling networks involved in immune cell function. Knockout studies suggest a role in regulating inflammatory responses and immune homeostasis, particularly in myeloid and lymphoid lineages.

Características del producto

category

ELISA Kits


immunogen target

GRB2 Associated Binding Protein 3 (GAB3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

GAB3,GRB2-associated binder 3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

GAB3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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