Human GRB2 Associated Binding Protein 3 (GAB3) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GAB3
proveedor
Abbexareference
abx387456Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human GRB2 Associated Binding Protein 3 (GAB3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GRB2 Associated Binding Protein 3 concentrations in serum, plasma and other biological fluids.
Background
GAB3 is an adaptor protein structurally related to GAB1 and GAB2, functioning downstream of receptor tyrosine kinases to activate pathways like PI3K/Akt and MAPK/ERK. It is primarily expressed in hematopoietic cells and immune tissues, where it regulates cell survival, proliferation, and differentiation. GAB3 supports B-cell receptor (BCR) and cytokine-mediated signaling, playing a role in B-cell development and macrophage activation. Its dysregulation is associated with altered immune responses and hematopoietic disorders. GAB3 interacts with SH2-containing proteins to modulate signaling networks involved in immune cell function. Knockout studies suggest a role in regulating inflammatory responses and immune homeostasis, particularly in myeloid and lymphoid lineages.
Características del producto
category
ELISA Kits
immunogen target
GRB2 Associated Binding Protein 3 (GAB3)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
GAB3,GRB2-associated binder 3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GAB3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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