Human Gp130/IL6ST (Interleukin-6 receptor subunit beta) ELISA Kit
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Name
Human Gp130/IL6ST (Interleukin-6 receptor subunit beta) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH0154
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.25-16ng/ml |
| Sensitivity | 0.15ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P40189 |
| Alias | Interleukin-6 receptor subunit beta,CD130,GP130,HIES4,IMD94,STWS2,CDW130,HIES4A,HIES4B,IL-6RB,Sgp130,IL-6R subunit beta,IL-6R-beta,IL-6RB,Membrane glycoprotein 130,Oncostatin-M receptor subunit alpha |
| Background | Elisa kits for IL6ST |
| Status | RUO |
Background
The interleukin 6 signal transducer (IL6ST), also known as gp130 or CD130, is a transmembrane protein that plays a crucial role in immune system regulation and cellular signaling. It functions as a common signal transducer for the IL-6 family of cytokines, which includes IL-6, IL-11, leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), and others. These cytokines are involved in various physiological processes, including immune responses, hematopoiesis, inflammation, and tissue regeneration. IL6ST/gp130 is a key receptor component in the JAK/STAT signaling pathway and is widely expressed in various cell types, including immune cells, neurons, hepatocytes, and endothelial cells. Its broad expression and signaling capability allow it to mediate responses across different tissues, contributing to a range of cellular functions such as proliferation, differentiation, survival, and apoptosis. Dysregulation of gp130 signaling has been associated with multiple conditions, including autoimmune diseases, chronic inflammatory disorders, and various cancers.
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