Human Gonadotropin Releasing Hormone Receptor 2 (Pseudogene) (GNRHR2) ELISA Kit

Este producto es parte de GNRHR - Gonadotropin Releasing Hormone Receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Gonadotropin Releasing Hormone Receptor 2 (Pseudogene) (GNRHR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx387618
tested applications
ELISA

Description

Human Gonadotropin Releasing Hormone Receptor 2 (Pseudogene) (GNRHR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GNRHR2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetGonadotropin Releasing Hormone Receptor 2 (Pseudogene) (GNRHR2)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.313 ng/ml - 20 ng/ml
Sensitivity< 0.188 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ96P88
OMIM612875
AliasGNRHR2,Type II GnRHR,gonadotropin-releasing hormone (type 2) receptor 2,gonadotropin-releasing hormone (type 2) receptor 2 pseudogene,GNRHR2P,GnRH-II-R,GnRH2 receptor
BackgroundElisa kits for GNRHR2
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

GNRHR2 is a paralog of GNRHR and a putative G protein-coupled receptor with structural similarity to the type 1 receptor (GNRHR). While GNRHR2 is functional in non-mammalian vertebrates, its role in humans remains controversial, as the gene is considered a pseudogene in some populations. However, evidence suggests that truncated or alternatively spliced variants of GNRHR2 may be expressed in human tissues, including the reproductive system, placenta, and certain tumors. GNRHR2 has been implicated in reproductive signaling and gonadotropin regulation, though its downstream signaling pathways and physiological relevance remain poorly characterized. Emerging studies indicate that GNRHR2 could play roles in regulating steroidogenesis, fertility, and tumor biology. Its expression in cancers, such as prostate and breast tumors, highlights its potential role in cell proliferation and survival. While the function of GNRHR2 in humans remains an active area of research, it holds promise for understanding reproductive signaling and its therapeutic implications in hormone-related diseases.

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