Human Glycoprotein 5 (GP5) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Glycoprotein 5 (GP5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168227
tested applications
WB, SDS-PAGE
Description
Glycoprotein V, Platelet Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Glycoprotein 5 (GP5) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln17-Pro242 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40197 |
| Alias | GPV,CD42d,Platelet glycoprotein V,GPV,Glycoprotein 5,CD42d |
| Background | Protein GP5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Glycoprotein V (GP5) is a key platelet membrane protein that functions as a part of the GPIb-IX-V complex, a receptor system primarily responsible for mediating platelet adhesion during vascular injury. This complex is crucial for the initial steps of platelet plug formation, which is essential in the process of hemostasis, particularly in the high-shear conditions of arterial blood flow. GP5 serves as an accessory component in the complex, complementing the roles of other glycoproteins like GPIbα (GP1BA), GPIbβ (GP1BB), and GPIX (GP9). The GPIb-IX-V complex, including GP5, binds to von Willebrand factor (vWF), which facilitates platelet tethering to the damaged endothelium under conditions of high shear stress. Although GP5 is not the primary binding site for vWF (that role belongs to GP1BA), it contributes to the structural integrity and function of the receptor. GP5 may also interact with other ligands and is thought to regulate the binding activity of the GPIb-IX-V complex.
Related Products
Human GP5 (Platelet glycoprotein V) ELISA Kit
Ver Producto
Mouse Glycoprotein 5 (GP5) Protein
Recombinant Glycoprotein V, Platelet (GP5) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Ver Producto