Human GLUD1(Glutamate dehydrogenase 1, mitochondrial) ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.625-40mIU/ml |
Size 1 | 96T |
Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 6 months |
UniProt ID | P00367 |
Alias | GLUD1|Glutamate dehydrogenase 1|mitochondrial|GDH 1|GLUD |
Background | Elisa Kits GLUD1 |
Status | RUO |
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Human GLUD1(Glutamate dehydrogenase 1, mitochondrial) ELISA Kit
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anti- GLUD1 antibody
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
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