Human GGT5 (Gamma glutamyltransferase 5) ELISA Kit
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Name
Human GGT5 (Gamma glutamyltransferase 5) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH8768
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P36269 |
| Alias | GGL,GGT 5,GGT-REL,GGTLA1 |
| Background | Elisa kits for GGT5 |
| Status | RUO |
Background
Gamma-glutamyltransferase 5 (GGT5) is an enzyme that cleaves gamma-glutamyl bonds in glutathione and other gamma-glutamyl compounds, facilitating glutathione metabolism and amino acid transport GGT5 is primarily expressed in the kidney, liver, and immune cells where it regulates extracellular glutathione breakdown and amino acid uptake for cellular antioxidant defense and detoxification pathways GGT5 plays a role in maintaining redox homeostasis by recycling glutathione, a key molecule for combating reactive oxygen species (ROS) Dysregulation of GGT5 expression has been associated with inflammatory conditions, cardiovascular diseases, and metabolic disorders Elevated GGT5 levels have also been observed in cancers, such as liver and renal cancers, where enhanced glutathione metabolism supports tumor progression and resistance to oxidative stress Additionally, GGT5 is involved in immune responses, as it regulates lymphocyte activation and macrophage function Its role in glutathione metabolism, cellular detoxification, and immune regulation underscores its importance in maintaining cellular health and redox balance across various physiological and pathological conditions
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