Human Gamma-Glutamyltransferase 5 (gGT5) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Gamma-Glutamyltransferase 5 (gGT5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166731
tested applications
WB, SDS-PAGE
Description
Gamma-Glutamyltransferase 5 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Gamma-Glutamyltransferase 5 (gGT5) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 24.5 kDa Observed MW (SDS-PAGE): 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr388-Tyr586 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | GGL,GGT 5,GGT-REL,GGTLA1 |
| Background | Protein GGT5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Gamma-glutamyltransferase 5 (GGT5) is an enzyme that cleaves gamma-glutamyl bonds in glutathione and other gamma-glutamyl compounds, facilitating glutathione metabolism and amino acid transport GGT5 is primarily expressed in the kidney, liver, and immune cells where it regulates extracellular glutathione breakdown and amino acid uptake for cellular antioxidant defense and detoxification pathways GGT5 plays a role in maintaining redox homeostasis by recycling glutathione, a key molecule for combating reactive oxygen species (ROS) Dysregulation of GGT5 expression has been associated with inflammatory conditions, cardiovascular diseases, and metabolic disorders Elevated GGT5 levels have also been observed in cancers, such as liver and renal cancers, where enhanced glutathione metabolism supports tumor progression and resistance to oxidative stress Additionally, GGT5 is involved in immune responses, as it regulates lymphocyte activation and macrophage function Its role in glutathione metabolism, cellular detoxification, and immune regulation underscores its importance in maintaining cellular health and redox balance across various physiological and pathological conditions
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