Human G-Protein Coupled Receptor 151 (GPR151) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human G-Protein Coupled Receptor 151 (GPR151) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650476
tested applications
WB, SDS-PAGE
Description
Human GPR151 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | G-Protein Coupled Receptor 151 (GPR151) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 16.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val308-Lys419 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TDV0 |
| Gene ID | 134391 |
| OMIM | 618487 |
| Alias | GPR151,GALR4,G-protein coupled receptor PGR7,galanin receptor 4,GALRL, GPCR, GPCR-2037, PGR7 |
| Background | Protein GPR151 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
GPR151 is an orphan G protein-coupled receptor (GPCR) predominantly expressed in the central nervous system, particularly in regions such as the habenula, a brain area involved in regulating mood, reward, and aversion responses. GPR151 is thought to play a role in modulating neuronal signaling pathways associated with addiction, anxiety, and depression. Its expression is tightly regulated by neuronal activity, suggesting it may function in fine-tuning synaptic signaling and maintaining neural circuit stability. Emerging evidence indicates that GPR151 is involved in behaviors linked to motivation, pain regulation, and responses to negative stimuli, particularly through its role in habenular circuits. Dysregulation of GPR151 expression has been associated with psychiatric disorders, including depression and substance abuse, where impaired habenular function disrupts mood and reward processing. Although its endogenous ligand remains unknown, GPR151 is considered a promising target for understanding mood disorders, addiction, and motivational behavior, highlighting its potential for therapeutic interventions in neuropsychiatric diseases.
Related Products
G-Protein Coupled Receptor 151 (GPR151) Antibody
Rabbit polyclonal antibody against GPR151. Immunogen region is C-terminal.
Ver Producto
G-Protein Coupled Receptor 151 (GPR151) Antibody
G-Protein Coupled Receptor 151 / GALR4 Antibody is a Rabbit Polyclonal against G-Protein Coupled Receptor 151 / GALR4.
Ver Producto