Human GABARAPL1 (Gamma-aminobutyric acid receptor-associated protein-like 1) ELISA Kit
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name
Human GABARAPL1 (Gamma-aminobutyric acid receptor-associated protein-like 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH8644
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9H0R8 |
| Alias | APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1 |
| Background | Elisa kits for GABARAPL1 |
| Status | RUO |
GABARAPL1 is a member of the GABARAP (GABA-A receptor-associated protein) family, which plays a key role in intracellular trafficking, autophagy, and receptor regulation. It facilitates the transport and membrane localization of GABA-A receptors, contributing to inhibitory neurotransmission in the central nervous system. Beyond its role in neurotransmitter signaling, GABARAPL1 is a critical component of the autophagy machinery, interacting with ATG proteins to regulate autophagosome formation and cargo sequestration. It is involved in cellular homeostasis, protein degradation, and stress responses. Dysregulation of GABARAPL1 has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, where impaired autophagy disrupts protein clearance and neuronal survival. GABARAPL1 is also implicated in cancer, where altered expression influences tumor progression, survival, and chemoresistance through autophagy modulation. Its dual role in receptor trafficking and autophagy highlights GABARAPL1 as a critical regulator of cellular and neuronal function, making it a potential therapeutic target in neurodegeneration and cancer.
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