Human Fructose Bisphosphate Aldolase B (ALDOB) Protein
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935106861
info@markelab.com
Precio
234€ (5 µg)
Protein ALDOB
proveedor
Abbexareference
abx073269Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Aldolase B Fructose-Bisphosphate is a recombinant enzyme.
Background
ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Fructose Bisphosphate Aldolase B (ALDOB)
host
E. coli
form
Liquid
tested applications
SDS-PAGE
size 1
5 µg
size 2
20 µg
size 3
1 mg
observerd MW
Molecular Weight: 42 kDa Concentration: 1 mg/ml Sequence Fragment: 1-364 AA. Tag: N-terminal His tag
expression
Recombinant
purity
> 95% (SDS-PAGE)
purification
Purified by proprietary chromatographic techniques.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
20 mM Tris-HCl buffer, pH 8.0, 1 mM DTT, 10% glycerol and 0.1 M NaCl
storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
ALDOB
dry ice
No
availability
Shipped within 5-10 working days.
alias
ALDOB,ALDB
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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