Human Fructose Bisphosphate Aldolase B (ALDOB) Protein

Este producto es parte de ALDOB - Fructose-Bisphosphate Aldolase B
Product Graph
234€ (5 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Fructose Bisphosphate Aldolase B (ALDOB) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073269
tested applications
SDS-PAGE

Description

Aldolase B Fructose-Bisphosphate is a recombinant enzyme.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Fructose Bisphosphate Aldolase B (ALDOB)
Host
E. coli
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Human
Observed MW
Molecular Weight: 42 kDa

Concentration: 1 mg/ml

Sequence Fragment: 1-364 AA.

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Purification
Purified by proprietary chromatographic techniques.
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Buffer
20 mM Tris-HCl buffer, pH 8.0, 1 mM DTT, 10% glycerol and 0.1 M NaCl
Availability
Shipped within 5-10 working days.
Storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P05062
Alias
ALDOB,ALDB
Background
Protein ALDOB
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.

Related Products

EH4806

Human Aldolase B ELISA Kit

Ver Producto
EM1969

Mouse ALDOB (Fructose-bisphosphate aldolase B) ELISA Kit

Ver Producto
FNab00302

ALDOB antibody

Ver Producto