Human Fructose Bisphosphate Aldolase B (ALDOB) Protein

Este producto es parte de ALDOB - Fructose-Bisphosphate Aldolase B
Human Fructose Bisphosphate Aldolase B (ALDOB) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (5 µg)

Protein ALDOB

proveedor

Abbexa

reference

abx073269

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Aldolase B Fructose-Bisphosphate is a recombinant enzyme.


Background

ALDOB is a liver-specific isoform of fructose-bisphosphate aldolase that primarily participates in fructose metabolism. It catalyzes the breakdown of fructose-1,6-bisphosphate and fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde, which are intermediates in glycolysis and gluconeogenesis. ALDOB is highly expressed in the liver, kidney, and small intestine. Mutations in ALDOB result in hereditary fructose intolerance (HFI), an autosomal recessive disorder characterized by the toxic accumulation of fructose-1-phosphate, leading to hypoglycemia, hepatomegaly, and renal dysfunction. ALDOB’s critical role in fructose metabolism highlights its importance in dietary sugar processing and maintaining energy balance.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Fructose Bisphosphate Aldolase B (ALDOB)


host

E. coli


form

Liquid


tested applications

SDS-PAGE


size 1

5 µg


size 2

20 µg


size 3

1 mg


observerd MW

Molecular Weight: 42 kDa Concentration: 1 mg/ml Sequence Fragment: 1-364 AA. Tag: N-terminal His tag


expression

Recombinant


purity

> 95% (SDS-PAGE)


purification

Purified by proprietary chromatographic techniques.


recommended dilution

Optimal dilutions/concentrations should be determined by the end user.


buffer

20 mM Tris-HCl buffer, pH 8.0, 1 mM DTT, 10% glycerol and 0.1 M NaCl


storage

Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.


or code

ALDOB


dry ice

No


availability

Shipped within 5-10 working days.


alias

ALDOB,ALDB


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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Tested Applications

ELISA, WB, IHC, IF, IP

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status

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clonality

polyclonal

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