Human Frizzled Homolog 6 (FZD6) ELISA Kit
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Description
Human Frizzled Homolog 6 (FZD6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Frizzled Homolog 6 (FZD6) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Frizzled Homolog 6 (FZD6)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Frizzled Homolog 6 (FZD6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.12 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | FZD6,FZ6,FZ-6,HFZ6,NDNC1,NDNC10,frizzled family receptor 6 |
| Background | Elisa kits for FZD6 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FZD6 is a non-canonical Wnt receptor primarily involved in planar cell polarity (PCP) signaling, which regulates cell orientation and migration. It is expressed in epithelial tissues, hair follicles, and the nervous system, where it controls processes like cell polarity, tissue morphogenesis, and embryonic development. FZD6 is essential for hair follicle orientation and skin development, as mutations in FZD6 are associated with conditions like nail dysplasia and abnormal hair patterns. In cancer, FZD6 is upregulated in gastric, breast, and ovarian cancers, where it promotes epithelial-mesenchymal transition (EMT), cell migration, and metastasis through non-canonical signaling pathways. FZD6 also regulates actin cytoskeleton dynamics, contributing to cell motility and invasion. In the nervous system, FZD6 influences neuronal development and axon guidance, highlighting its role in neurodevelopmental processes. Dysregulation of FZD6 signaling leads to developmental defects and cancer progression. Its function in PCP signaling and cytoskeletal regulation positions FZD6 as a key target for therapies aimed at modulating cell polarity, tissue architecture, and cancer metastasis.
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Human Frizzled Homolog 6 (FZD6) ELISA Kit
Human Frizzled Homolog 6 (FZD6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Frizzled Homolog 6 (FZD6) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Frizzled Homolog 6 (FZD6)
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