Human Follistatin-Related Protein 5 (FSTL5) Protein
1235€ (100 µg)
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935106861
info@markelab.com
name
Human Follistatin-Related Protein 5 (FSTL5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692491
tested applications
SDS-PAGE
Description
Human FSTL5 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human FSTL5 (Q8N475) (Gln32-Ala847) was expressed with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Follistatin-Related Protein 5 (FSTL5) |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: 94.9 kDa Sequence Fragment: Gln32-Ala847 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N475 |
| Gene ID | 56884 |
| Alias | Follistatin-related protein 5,KIAA1263 |
| Background | Protein FSTL5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
FSTL5 is a secreted glycoprotein from the follistatin-related protein family, which regulates cell signaling pathways by interacting with members of the TGF-β superfamily, including activins and BMPs. FSTL5 is expressed in various tissues, with high levels in the brain, heart, and skeletal muscle, suggesting roles in neural and muscular development. It acts as a modulator of growth factor activity, influencing processes such as cell proliferation, differentiation, and apoptosis. In the central nervous system, FSTL5 is involved in synaptic regulation and may contribute to neuronal survival during stress or injury. Dysregulation of FSTL5 expression has been observed in certain cancers, where it is thought to influence tumor progression by altering the tumor microenvironment and promoting angiogenesis. Its multifunctional role in development, tissue repair, and disease progression underscores its importance in maintaining cellular homeostasis and its potential as a therapeutic target in oncology and regenerative medicine.
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