Follistatin-Related Protein 5 (FSTL5) Antibody

Este producto es parte de FSTL - Follistatin-like protein
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Follistatin-Related Protein 5 (FSTL5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027464
tested applications
ELISA, WB

Description

The function of this protein remains unknown.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetFollistatin-Related Protein 5 (FSTL5)
HostRabbit
ReactivityMouse
Recommended DilutionWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified through a protein A column, followed by peptide affinity purification.
Size 180 µl
Size 2400 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS containing 0.09% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8N475
Gene ID56884
AliasFollistatin-related protein 5,KIAA1263
BackgroundAntibody anti-FSTL5
StatusRUO
NoteConcentration: 0.50 mg/ml -

Descripción

FSTL5 is a secreted glycoprotein from the follistatin-related protein family, which regulates cell signaling pathways by interacting with members of the TGF-β superfamily, including activins and BMPs. FSTL5 is expressed in various tissues, with high levels in the brain, heart, and skeletal muscle, suggesting roles in neural and muscular development. It acts as a modulator of growth factor activity, influencing processes such as cell proliferation, differentiation, and apoptosis. In the central nervous system, FSTL5 is involved in synaptic regulation and may contribute to neuronal survival during stress or injury. Dysregulation of FSTL5 expression has been observed in certain cancers, where it is thought to influence tumor progression by altering the tumor microenvironment and promoting angiogenesis. Its multifunctional role in development, tissue repair, and disease progression underscores its importance in maintaining cellular homeostasis and its potential as a therapeutic target in oncology and regenerative medicine.

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