Human Follistatin-related protein 4 (FSTL4) ELISA Kit

Este producto es parte de FSTL - Follistatin-like protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Follistatin-related protein 4 (FSTL4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx524372
tested applications
ELISA

Description

Human Follistatin-related protein 4 (FSTL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Follistatin-related protein 4 (FSTL4) concentrations in serum, plasma and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Follistatin-related protein 4 (FSTL4)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6MZW2
Alias
Follistatin-related protein 4,KIAA1061
Background
Elisa kits for FSTL4
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

FSTL4 is a secreted glycoprotein that belongs to the SPARC family of extracellular matrix-associated proteins, which are involved in regulating cell signaling, differentiation, and tissue remodeling. FSTL4 contains a follistatin-like domain that enables it to interact with members of the TGF-β superfamily, particularly bone morphogenetic proteins (BMPs), modulating their activity in processes such as neural development and synaptic plasticity. It is predominantly expressed in neural tissues, including the brain and spinal cord, where it regulates neuronal signaling and connectivity. FSTL4 also plays a role in maintaining neural integrity and has been implicated in protecting neurons from excitotoxicity, a process linked to neurodegenerative diseases. Dysregulation of FSTL4 expression has been associated with cognitive deficits, as well as potential links to neuropsychiatric disorders such as autism spectrum disorder. Its structural features, including calcium-binding EF-hand domains, further enhance its regulatory roles in extracellular matrix interactions and cellular signaling pathways.

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