Human Folate Receptor Alpha (FOLR1) Protein

546€ (100 µg)
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name
Human Folate Receptor Alpha (FOLR1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620335
tested applications
ELISA, WB, SDS-PAGE
Description
Human Folate Receptor Alpha (FOLR1) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Folate Receptor Alpha (FOLR1) |
| Host | Mammalian cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Met233 Tag: C-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 28.19 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P15328 |
| Background | Protein FOLR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
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