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Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Primary Antibodies
polyclonal
human
folate receptor 1
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IF,IHC
38 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
FOLR1
Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1(adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha
This product is for research use only.
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