FOLR1 antibody
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935106861
info@markelab.com
name
FOLR1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03184
tested applications
ELISA, WB, IF,IHC
Description
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | folate receptor 1 (FOLR1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF,IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P15328 |
| Gene ID | 2348 |
| Alias | Folate receptor alpha (FR-alpha),Adult folate-binding protein (FBP),Folate receptor 1,Folate receptor, adult,KB cells FBP,Ovarian tumor-associated antigen MOv18,FOLR1,FOLR |
| Background | Antibody anti-FOLR1 |
| Status | RUO |
| Note | Mol. Weight 38 kDa |
Descripción
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FOLR1 antibody
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Ver Producto