Human Fibroblast Growth Factor Receptor Substrate 3 (FRS3) ELISA Kit

Este producto es parte de FRS - Fibroblast growth factor receptor substrate
Human Fibroblast Growth Factor Receptor Substrate 3 (FRS3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for FRS3

proveedor

Abbexa

reference

abx387421

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Fibroblast Growth Factor Receptor Substrate 3 (FRS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human FRS3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Fibroblast growth factor receptor substrate 3 (FRS3) is another adaptor protein involved in FGFR signaling pathways. Like FRS2, FRS3 becomes tyrosine-phosphorylated upon FGFR activation and serves as a scaffold for the assembly of signaling complexes. FRS3 interacts with various signaling proteins, including Grb2 and Sos, to activate the Ras/MAPK pathway, promoting cellular proliferation and differentiation. Although FRS3 shares functional similarities with FRS2, it is known for its distinct tissue distribution and specific engagement with particular FGFR isoforms. These unique interactions suggest that FRS3 may play specialized roles in certain biological contexts. FRS3's involvement in FGFR signaling also links it to developmental processes and pathological conditions such as cancer. Understanding FRS3's unique contributions to FGFR signaling can provide insights into its potential as a therapeutic target in diseases involving aberrant FGFR activity.

Características del producto

category

ELISA Kits


immunogen target

Fibroblast Growth Factor Receptor Substrate 3 (FRS3)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

FRS2-beta,FRS2B,FRS2beta,SNT-2,SNT2,FGFR substrate 3,FGFR-signaling adaptor SNT2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

FRS3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Rat FRS3(Fibroblast Growth Factor Receptor SubstRate 3) ELISA Kit

Rat FRS3(Fibroblast Growth Factor Receptor SubstRate 3) ELISA Kit

proveedor

FineTest

reference

ER0959

reactivity

rat

status

RUO

Precio a consultar

Ver más

anti- FRS3 antibody

anti- FRS3 antibody

proveedor

FineTest

reference

FNab03226

Tested Applications

ELISA, WB, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kin...

Precio a consultar

Ver más

Fibroblast Growth Factor Receptor Substrate 3 (FRS3) Antibody

Fibroblast Growth Factor Receptor Substrate 3 (FRS3) Antibody

proveedor

Abbexa

reference

abx014001

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Rabbit polyclonal antibody against FRS3 protein. Immunogen region is Internal.

52€ (10 µg)

Ver más