Human Fibroblast Growth Factor 21 (FGF21) Protein

Este producto es parte de FGF21 - Fibroblast Growth Factor 21
Human Fibroblast Growth Factor 21 (FGF21) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein FGF21

proveedor

Abbexa

reference

abx167077

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Fibroblast Growth Factor 21 Protein is a recombinant Human protein expressed in E. coli.


Background

FGF21 is a metabolic hormone belonging to the fibroblast growth factor family, primarily produced in the liver under conditions of fasting, stress, and ketogenic diet consumption. It regulates glucose metabolism, lipid homeostasis, and energy expenditure by activating FGF receptors in conjunction with the co-receptor β-Klotho. FGF21 enhances insulin sensitivity, promotes lipolysis in adipose tissue, and stimulates ketogenesis in the liver, making it a critical regulator during energy deficits. It has also been linked to reducing body weight and mitigating non-alcoholic fatty liver disease (NAFLD). Therapeutically, FGF21 analogs are being explored for treating type 2 diabetes, obesity, and metabolic disorders. Dysregulation of FGF21 has been observed in insulin resistance and cardiovascular diseases.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Fibroblast Growth Factor 21 (FGF21)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 23.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: His29-Ser209 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

FGF21


dry ice

No


availability

Shipped within 5-7 working days.


alias

FGF-21


NCBI accession

NP_061986.1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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