Fibroblast Growth Factor 21 (FGF21) Antibody

Este producto es parte de FGF21 - Fibroblast Growth Factor 21
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286€ (100 µl)

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935106861
info@markelab.com
name
Fibroblast Growth Factor 21 (FGF21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102850
tested applications
ELISA, WB, IHC, IF/ICC

Description

Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetFibroblast Growth Factor 21 (FGF21)
HostRabbit
ReactivityMouse
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
Size 1100 µl
Size 2200 µl
Size 31 ml
Tested ApplicationsELISA, WB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityShipped within 5-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9JJN1
Gene ID56636
AliasFGF-21
BackgroundAntibody anti-FGF21
StatusRUO

Descripción

FGF21 is a metabolic hormone belonging to the fibroblast growth factor family, primarily produced in the liver under conditions of fasting, stress, and ketogenic diet consumption. It regulates glucose metabolism, lipid homeostasis, and energy expenditure by activating FGF receptors in conjunction with the co-receptor β-Klotho. FGF21 enhances insulin sensitivity, promotes lipolysis in adipose tissue, and stimulates ketogenesis in the liver, making it a critical regulator during energy deficits. It has also been linked to reducing body weight and mitigating non-alcoholic fatty liver disease (NAFLD). Therapeutically, FGF21 analogs are being explored for treating type 2 diabetes, obesity, and metabolic disorders. Dysregulation of FGF21 has been observed in insulin resistance and cardiovascular diseases.

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