Human Fibroblast Growth Factor 21 (FGF21) CLIA Kit
643.5€ (96 tests)
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Name
Human Fibroblast Growth Factor 21 (FGF21) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx195625
Tested Applications
CLIA
Description
Human Fibroblast Growth Factor 21 (FGF21) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Fibroblast Growth Factor 21 (FGF21).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | CLIA Kits |
| Immunogen Target | Fibroblast Growth Factor 21 (FGF21) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 12.5 pg/ml - 800 pg/ml |
| Sensitivity | 7.5 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard: Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9NSA1 |
| Gene ID | 26291 |
| NCBI Accession | NP_061986.1 |
| OMIM | 609436 |
| Alias | FGF-21 |
| Background | CLIA Kits FGF21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
FGF21 is a metabolic hormone belonging to the fibroblast growth factor family, primarily produced in the liver under conditions of fasting, stress, and ketogenic diet consumption. It regulates glucose metabolism, lipid homeostasis, and energy expenditure by activating FGF receptors in conjunction with the co-receptor β-Klotho. FGF21 enhances insulin sensitivity, promotes lipolysis in adipose tissue, and stimulates ketogenesis in the liver, making it a critical regulator during energy deficits. It has also been linked to reducing body weight and mitigating non-alcoholic fatty liver disease (NAFLD). Therapeutically, FGF21 analogs are being explored for treating type 2 diabetes, obesity, and metabolic disorders. Dysregulation of FGF21 has been observed in insulin resistance and cardiovascular diseases.
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