Human Fibroblast Growth Factor 19 (FGF19) Protein

Este producto es parte de FGF19 - Fibroblast Growth Factor 19
Human Fibroblast Growth Factor 19 (FGF19) Protein

Pida mas información

935106861

info@markelab.com

Precio

225€ (5 µg)

Protein FGF19

proveedor

Abbexa

reference

abx262135

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Fibroblast Growth Factor 19 (FGF19) His Tag Protein is a recombinant cytokine.


Background

FGF19 is a metabolic hormone primarily produced in the ileum of the small intestine in response to bile acid signaling where it regulates bile acid homeostasis by suppressing cholesterol 7α-hydroxylase (CYP7A1) expression in the liver FGF19 also promotes glucose metabolism, lipid homeostasis, and energy expenditure through signaling pathways involving its receptor FGFR4 and the co-receptor β-Klotho Dysregulation of FGF19 has been linked to non-alcoholic fatty liver disease (NAFLD), insulin resistance, and obesity Elevated FGF19 levels are also observed in liver cancers such as hepatocellular carcinoma (HCC) where its overactivation promotes tumor growth by driving cell proliferation and survival FGF19 analogs are being explored as therapies for metabolic disorders, including type 2 diabetes and dyslipidemia

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Fibroblast Growth Factor 19 (FGF19)


host

E. coli


conjugation

Unconjugated


form

Lyophilized


tested applications

SDS-PAGE


size 1

5 µg


size 2

25 µg


size 3

1 mg


expression

Recombinant


purity

> 95% (SDS-PAGE)


purification

Purified by proprietary chromatographic techniques, followed by filtration (0.4 µm).


buffer

Prior to lyophilization: 20 mM Tris, 20 mM NaCl, pH 7.5.


storage

Stable at room temperature for up to 3 weeks. Store below -18 °C for long-term storage. Upon reconstitution, store at 4 °C for up to 7 days and store below -18 °C for long-term storage. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.


or code

FGF19


dry ice

No


availability

Shipped within 5-10 working days.


alias

FGF-19


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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