Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Protein
234€ (2 µg)
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935106861
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name
Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680179
tested applications
SDS-PAGE
Description
Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | CD16,FCG3,CD16A,CD16b,FCGR3,CD16-I,FCGR3A,FCR-10,FCRIII,FCRIIIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Fc-gamma RIII-beta,IgG Fc receptor III-1 |
| Background | Protein FCGR3B |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
FCGR3B, or Fc gamma receptor IIIb, is a low-affinity receptor for the Fc portion of immunoglobulin G (IgG) antibodies, primarily expressed on neutrophils. It is a member of the Fc gamma receptor (FcγR) family, which plays a pivotal role in mediating immune responses through the recognition of the Fc region of IgG antibodies. FCGR3B is one of the two isoforms of FcγRIII, the other being FCGR3A (CD16A). While both isoforms share sequence similarity and belong to the same gene family, they have distinct tissue distributions, membrane anchoring mechanisms, and functional roles in the immune system. FCGR3B is especially important for facilitating immune complex clearance, phagocytosis, and neutrophil activation, processes that are crucial in maintaining immune homeostasis and defending against pathogens. Dysregulation of FCGR3B or mutations in its gene have been associated with a range of clinical conditions, including autoimmune diseases and chronic inflammatory disorders
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