Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
587.5€ (96 tests)
Elisa Kits FCGR3B
proveedor
Abbexareference
abx252444Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
FCGR3B, or Fc gamma receptor IIIb, is a low-affinity receptor for the Fc portion of immunoglobulin G (IgG) antibodies, primarily expressed on neutrophils. It is a member of the Fc gamma receptor (FcγR) family, which plays a pivotal role in mediating immune responses through the recognition of the Fc region of IgG antibodies. FCGR3B is one of the two isoforms of FcγRIII, the other being FCGR3A (CD16A). While both isoforms share sequence similarity and belong to the same gene family, they have distinct tissue distributions, membrane anchoring mechanisms, and functional roles in the immune system. FCGR3B is especially important for facilitating immune complex clearance, phagocytosis, and neutrophil activation, processes that are crucial in maintaining immune homeostasis and defending against pathogens. Dysregulation of FCGR3B or mutations in its gene have been associated with a range of clinical conditions, including autoimmune diseases and chronic inflammatory disorders
Características del producto
category
ELISA Kits
immunogen target
Fc Fragment Of IgG Low Affinity IIIb Receptor (FCGR3B)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD16,FCG3,CD16A,CD16b,FCGR3,CD16-I,FCGR3A,FCR-10,FCRIII,FCRIIIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Fc-gamma RIII-beta,IgG Fc receptor III-1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FCGR3B
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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