Human Fc Fragment of IgG, Low Affinity IIb, Receptor / CD32 (FCGR2B) ELISA Kit

Este producto es parte de FCGR2B - Fc gamma receptor Iib
Human Fc Fragment of IgG, Low Affinity IIb, Receptor / CD32 (FCGR2B) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

493.75€ (96 tests)

Elisa Kits FCGR2B

proveedor

Abbexa

reference

abx250220

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Fc Fragment of IgG, Low Affinity IIb, Receptor / CD32 (FCGR2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fc Fragment of IgG, Low Affinity IIb, Receptor / CD32 (FCGR2B) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

FCGR2B (Fc gamma receptor IIB), also known as CD32B, is a low-affinity receptor for the Fc portion of IgG antibodies, primarily responsible for regulating immune responses by mediating inhibitory signaling. It plays a crucial role in the balance between activation and inhibition of immune cells, preventing excessive inflammation and autoimmunity. Unlike its closely related receptor, FCGR2A, which triggers activating signals, FCGR2B is the only inhibitory receptor within the Fc gamma receptor family. This receptor is predominantly expressed on B cells, dendritic cells, macrophages, and other immune cells. FCGR2B is part of the larger family of Fc gamma receptors (FcγRs), which bind the Fc region of immunoglobulin G (IgG) to mediate immune responses such as phagocytosis, cytokine release, and the clearance of immune complexes. Its inhibitory role is vital in the prevention of autoimmune reactions and the modulation of inflammatory responses.

Características del producto

category

ELISA Kits


immunogen target

Fc Fragment of IgG, Low Affinity IIb, Receptor / CD32 (FCGR2B)


reactivity

Human


test range

46.88 pg/ml - 3000 pg/ml


sensitivity

28.13 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

CD32,FCG2,CD32B,FCGR2,IGFR2,FCGR2C,FcGRIIB,FcRII-c,FcgammaRIIb,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

FCGR2B


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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