Human Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Protein
169€ (10 µg)
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name
Human Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650633
tested applications
WB, SDS-PAGE
Description
Human EEF1E1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu14-His174 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43324 |
| Gene ID | 9521 |
| OMIM | 609206 |
| Alias | AIMP3, P18,EEF1E1 |
| Background | Protein EEF1E1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
EEF1E1 is a subunit of the eukaryotic elongation factor 1 (eEF1) complex, which plays a critical role in protein synthesis by facilitating the recruitment of aminoacyl-tRNA to the ribosome during elongation. EEF1E1 functions as a structural component, stabilizing the interaction between other subunits, such as EEF1A and EEF1B, within the eEF1 complex. It is also involved in regulating the exchange of GDP for GTP on EEF1A, a critical step in elongation cycle progression. EEF1E1 is expressed ubiquitously, reflecting its essential role in maintaining efficient protein translation in all cells. Dysregulation of EEF1E1 has been linked to cancer progression, where increased protein synthesis supports tumor growth and proliferation. It is also implicated in neurodegenerative diseases, where disruptions in protein homeostasis and elongation factor function are contributing factors. Further studies are needed to explore its broader roles in translational control and disease pathology.
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