Human Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Protein
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935106861
info@markelab.com
Precio
169€ (10 µg)
Protein EEF1E1
proveedor
Abbexareference
abx650633Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human EEF1E1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
EEF1E1 is a subunit of the eukaryotic elongation factor 1 (eEF1) complex, which plays a critical role in protein synthesis by facilitating the recruitment of aminoacyl-tRNA to the ribosome during elongation. EEF1E1 functions as a structural component, stabilizing the interaction between other subunits, such as EEF1A and EEF1B, within the eEF1 complex. It is also involved in regulating the exchange of GDP for GTP on EEF1A, a critical step in elongation cycle progression. EEF1E1 is expressed ubiquitously, reflecting its essential role in maintaining efficient protein translation in all cells. Dysregulation of EEF1E1 has been linked to cancer progression, where increased protein synthesis supports tumor growth and proliferation. It is also implicated in neurodegenerative diseases, where disruptions in protein homeostasis and elongation factor function are contributing factors. Further studies are needed to explore its broader roles in translational control and disease pathology.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 22.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu14-His174 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
EEF1E1
dry ice
No
availability
Shipped within 5-7 working days.
alias
AIMP3, P18,EEF1E1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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