Human Endothelin 1 (EDN1) Peptide
234€ (1 mg)
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Name
Human Endothelin 1 (EDN1) Peptide
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx265082
Description
Endothelin-1 is a peptide.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Endothelin 1 (EDN1) |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 2491.95 Da |
| Purity | > 95% (HPLC) |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Size 3 | 10 mg |
| Form | Lyophilized |
| Buffer | Not applicable. |
| Availability | Shipped within 10-20 working days. |
| Storage | Store dry at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ARCND3,ET1, ET-1,HDLCQ7,QME,PPET1 |
| Background | Protein EDN1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Endothelin-1 (EDN1) is a peptide hormone belonging to the endothelin family. It plays a crucial role in regulating blood vessel contraction and dilation, thereby influencing blood pressure and blood flow throughout the body. Endothelin-1 is primarily produced by endothelial cells, It is also produced by other cell types, including vascular smooth muscle cells, cardiomyocytes, and certain inflammatory cells.Endothelin-1 acts as a potent vasoconstrictor, meaning it causes blood vessels to narrow, leading to an increase in blood pressure. Dysregulation of endothelin-1 signaling is associated with several cardiovascular disorders, including hypertension, atherosclerosis, coronary artery disease, and pulmonary hypertension. Elevated levels of endothelin-1 have been observed in individuals with these conditions, contributing to their pathogenesis. Endothelin-1 is able to bind to specific receptors on target cells known as endothelin receptors. There are two main types of endothelin receptors: endothelin receptor type A (ETA) and endothelin receptor type B (ETB).
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