Human EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) Protein
234€ (10 µg)
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935106861
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name
Human EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650787
tested applications
WB, SDS-PAGE
Description
Human EMR1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | EGF Like Module Containing Mucin Like Hormone Receptor 1 (EMR1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Pro201 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14246 |
| Alias | ADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3 |
| Background | Protein ADGRE1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.
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