EGF-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 (Emr1) Antibody
637€ (100 µl)
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Name
EGF-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 (Emr1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx112246
Tested Applications
ELISA, WB
Description
Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 Antibody is a Rabbit Polyclonal antibody against Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: EGF-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 (Emr1) Immunogen: Human F4-80. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14246 |
| Gene ID | 2015 |
| NCBI Accession | NM_001974.4 |
| OMIM | 600493 |
| Alias | ADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3 |
| Background | Antibody anti-ADGRE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.
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