Human Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1) Protein (Active)
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Description
Human DCAMKL1 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the human DCLK1 (O15075-1) (Met 1-Val 705) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | DCAMKL1 |
| Host | Insect |
| Origin | Human |
| Observed MW | Molecular Weight: 106 kDa Sequence Fragment: Met1-Val705 Tag: N-terminal His tag and GST tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 84% (SDS-PAGE) |
| Size 1 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly, 0.5mM PMSF. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15075-1 |
| Background | Protein DCAMKL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Doublecortin-Like And CAM Kinase-Like 1 (DCAMKL1) Antibody
Doublecortin-like kinase (DCAMKL1) (Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.
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Human DCAMKL1 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the human DCLK1 (O15075-1) (Met 1-Val 705) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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