Human Dopamine Receptor D3 (DRD3) ELISA Kit

Este producto es parte de DRD - Dopamine Receptor D
Human Dopamine Receptor D3 (DRD3) ELISA Kit
546€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Dopamine Receptor D3 (DRD3) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx570089
Tested Applications
ELISA

Description

Human Dopamine Receptor D3 (DRD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Dopamine Receptor D3 (DRD3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Dopamine Receptor D3 (DRD3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.31 ng/ml - 20 ng/ml
Sensitivity
0.19 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P35462
Alias
DRD3,D3DR,ETM1,FET1,D3 receptor,dopamine D3 receptor,dopaminergic receptor D3
Background
Elisa Kits for: DRD3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

DRD3 is a G protein-coupled receptor (GPCR) of the D2-like family that couples to Gi/o proteins, inhibiting adenylate cyclase activity and reducing intracellular cyclic AMP (cAMP) levels. It is primarily expressed in limbic regions of the brain, including the ventral striatum, nucleus accumbens, and olfactory tubercle, where it regulates emotional behavior, reward processing, and cognitive function. DRD3 is involved in motivation, reinforcement learning, and drug addiction, where its dysregulation contributes to compulsive behaviors and substance abuse disorders. In schizophrenia, altered DRD3 signaling is associated with cognitive and behavioral deficits, and it is a target for atypical antipsychotics. DRD3 also plays a role in Parkinson’s disease, where it regulates motor control and is upregulated in response to dopaminergic neuron loss, contributing to dyskinesia. Outside the brain, DRD3 is expressed in peripheral tissues, including the kidney and immune cells, where it influences renal function and immune responses. DRD3 is a promising therapeutic target for neuropsychiatric disorders, Parkinson’s disease, and addiction, with specific agonists and antagonists under development to modulate its function.

Productos relacionados

abx001308

Dopamine Receptor D3 (DRD3) Antibody

DRD3 Antibody is a Rabbit Polyclonal antibody against DRD3. This gene encodes the D3 subtype of the five (D1-D5) dopamin…

Ver producto
abx151340

Human Dopamine Receptor D3 (DRD3) ELISA Kit

Human Dopamine Receptor D3 (DRD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Dopamine …

Ver producto
abx196914

Rat Dopamine Receptor D3 (DRD3) CLIA Kit

Rat Dopamine Receptor D3 (DRD3) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit aga…

Ver producto