Human Dopamine Receptor D1 (DRD1) ELISA Kit

Este producto es parte de DRD - Dopamine Receptor D
Human Dopamine Receptor D1 (DRD1) ELISA Kit
585€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Dopamine Receptor D1 (DRD1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx250754
Tested Applications
ELISA

Description

Human Dopamine Receptor D1 (DRD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Dopamine Receptor D1 (DRD1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Dopamine Receptor D1 (DRD1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.31 ng/ml - 20 ng/ml
Sensitivity
0.19 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P21728
Alias
DRD1,D1A,DADR,Gpcr15,dopamine D1 receptor,Dopamine-1A receptor,D1 receptor,Drd-1,Drd1a
Background
Elisa Kits for: DRD1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

DRD1 is a G protein-coupled receptor (GPCR) that belongs to the D1-like receptor family and is the most abundant dopamine receptor in the central nervous system (CNS). It is primarily expressed in brain regions such as the striatum, prefrontal cortex, and hippocampus, where it modulates motor control, cognition, and reward signaling. DRD1 couples to Gs proteins, leading to activation of adenylate cyclase, which increases intracellular cyclic AMP (cAMP) levels and activates protein kinase A (PKA) pathways. DRD1 signaling enhances synaptic plasticity, learning, and memory formation and plays a key role in mediating motivation and reinforcement behaviors. Dysregulation of DRD1 activity has been implicated in neuropsychiatric disorders, including schizophrenia, attention-deficit hyperactivity disorder (ADHD), and drug addiction, where abnormal dopaminergic transmission disrupts behavior and cognition. In Parkinson’s disease, reduced DRD1 signaling contributes to motor dysfunction due to dopamine depletion. DRD1 is also involved in cardiovascular regulation and renal function, influencing blood pressure and sodium balance. Pharmacological targeting of DRD1 with agonists or antagonists has therapeutic potential for neurological disorders, such as Parkinson’s and schizophrenia, as well as cardiovascular conditions.

Productos relacionados

abx002124

Dopamine Receptor D1 (DRD1) Antibody

DRD1 Antibody is a Rabbit Polyclonal antibody against DRD1. This gene encodes the D1 subtype of the dopamine receptor. T…

Ver producto
abx022553

Dopamine Receptor D1 (DRD1) Antibody

D1 Dopamine Receptor Antibody is a Rabbit polyclonal antibody for neuroscience against D1 Dopamine Receptor.…

Ver producto
abx052929

Human Dopamine Receptor D1 (DRD1) ELISA Kit

Human Dopamine Receptor D1 (DRD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Dopamine …

Ver producto