Human Docking Protein 4 (DOK4) ELISA Kit

Este producto es parte de DOK - Docking protein
Human Docking Protein 4 (DOK4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOK4

proveedor

Abbexa

reference

abx386970

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Docking Protein 4 (DOK4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOK4 concentrations in serum, plasma and other biological fluids.


Background

DOK4 is an adaptor protein belonging to the DOK family, involved in signal transduction downstream of receptor tyrosine kinases, such as RET and insulin receptors. It modulates pathways like MAPK/ERK and PI3K/Akt, influencing cellular proliferation, survival, and differentiation. DOK4 is expressed in tissues like skeletal muscle, adipose tissue, and the nervous system, where it regulates metabolic signaling and cellular responses. It acts as a negative regulator of signaling by binding to SH2 domains and inhibiting downstream activation. Dysregulation of DOK4 is associated with metabolic disorders, insulin resistance, and certain cancers, where it influences cell adhesion and motility.

Características del producto

category

ELISA Kits


immunogen target

Docking Protein 4 (DOK4)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

Downstream of tyrosine kinase 4,Insulin receptor substrate 5,IRS-5,IRS5


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOK4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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