Human Disintegrin and metalloproteinase domain-containing protein 7 (ADAM7) ELISA Kit

Este producto es parte de ADAM7 - ADAM metallopeptidase domain 7
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Disintegrin and metalloproteinase domain-containing protein 7 (ADAM7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501033
tested applications
ELISA

Description

Human Disintegrin and metalloproteinase domain-containing protein 7 (ADAM7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Disintegrin and metalloproteinase domain-containing protein 7 (ADAM7) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetDisintegrin and metalloproteinase domain-containing protein 7 (ADAM7)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ9H2U9
AliasEAPI, GP83,ADAM-7
BackgroundElisa kits for ADAM7
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADAM7 is a member of the ADAMs family, a group distinguished by their zinc protease activity. These transmembrane proteins serve as pivotal players in a myriad of biological processes, orchestrating vital functions such as cell signaling, adhesion, and migration. Despite its classification as a zinc protease, the protein encoded by ADAM7 intriguingly lacks typical protease activity. Instead, it likely operates through mediating protein-protein interactions, thereby modulating essential cellular processes such as cell adhesion. Of particular interest is its potential involvement in facilitating protein-protein interactions and cell adhesion events, including the intricate process of sperm-egg fusion. Through its participation in these adhesive mechanisms, ADAM7 may act as a facilitator in the complex interplay between sperm and egg, ultimately contributing to successful fertilization. Moreover, emerging studies suggest a connection between mutations in the ADAM7 gene and the progression of melanoma, a highly aggressive form of skin cancer. These mutations are hypothesized to disrupt the protein's normal functioning, potentially leading to dysregulated cell adhesion processes and promoting the uncontrolled growth and metastasis of melanoma cells.

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