Human DENN domain-containing protein 2D (DENND2D) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human DENN domain-containing protein 2D (DENND2D) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx510098
tested applications
ELISA
Description
Human DENN domain-containing protein 2D (DENND2D) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DENN domain-containing protein 2D (DENND2D) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DENN domain-containing protein 2D (DENND2D) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9H6A0 |
| Alias | DENND2D |
| Background | Elisa kits for DENND2D |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DENN domain containing 2D (DENND2D) is a guanine nucleotide exchange factor (GEF) within the DENN protein family, specifically targeting Rab GTPases, including Rab9. DENND2D plays a pivotal role in retrograde transport by activating Rab9 to facilitate vesicle movement between late endosomes and the trans-Golgi network. This transport is critical for recycling membrane proteins, maintaining lysosomal enzyme trafficking, and regulating receptor degradation. DENND2D is involved in cellular processes such as autophagy, endosomal sorting, and signaling pathways linked to cellular stress and growth. Its expression pattern suggests a broad functional relevance, particularly in tissues with active vesicular transport systems. Mutations or dysregulation of DENND2D have been associated with lysosomal storage disorders and other conditions resulting from impaired vesicle trafficking, underlining its importance in cellular health and homeostasis.
Related Products
DENN Domain-Containing Protein 2D (DENND2D) Antibody
DENND2D Antibody is a Rabbit Polyclonal against DENND2D.
Ver ProductoDENND2D Antibody (HRP)
DENND2D Antibody (HRP) is a Rabbit Polyclonal against DENND2D conjugated to HRP.
Ver Producto
DENND2D Antibody (FITC)
DENND2D Antibody (FITC) is a Rabbit Polyclonal against DENND2D conjugated to FITC.
Ver Producto