Human DENN domain-containing protein 2D (DENND2D) ELISA Kit

Este producto es parte de DENND - DENN domain containing
Human DENN domain-containing protein 2D (DENND2D) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DENND2D

proveedor

Abbexa

reference

abx510098

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human DENN domain-containing protein 2D (DENND2D) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DENN domain-containing protein 2D (DENND2D) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DENN domain containing 2D (DENND2D) is a guanine nucleotide exchange factor (GEF) within the DENN protein family, specifically targeting Rab GTPases, including Rab9. DENND2D plays a pivotal role in retrograde transport by activating Rab9 to facilitate vesicle movement between late endosomes and the trans-Golgi network. This transport is critical for recycling membrane proteins, maintaining lysosomal enzyme trafficking, and regulating receptor degradation. DENND2D is involved in cellular processes such as autophagy, endosomal sorting, and signaling pathways linked to cellular stress and growth. Its expression pattern suggests a broad functional relevance, particularly in tissues with active vesicular transport systems. Mutations or dysregulation of DENND2D have been associated with lysosomal storage disorders and other conditions resulting from impaired vesicle trafficking, underlining its importance in cellular health and homeostasis.

Características del producto

category

ELISA Kits


immunogen target

DENN domain-containing protein 2D (DENND2D)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DENND2D


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DENND2D


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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