Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOCK9

proveedor

Abbexa

reference

abx386966

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Dedicator Of Cytokinesis Protein 9 (DOCK9) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOCK9 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DOCK9, also known as Zizimin1, functions as a GEF for Cdc42, regulating actin remodeling, filopodia formation, and cell polarity. It is widely expressed in tissues, including the brain, where it controls neurite outgrowth, axonal guidance, and synaptic development. DOCK9 interacts with membrane phosphoinositides like PIP3 for activation, linking signaling pathways to cytoskeletal changes. It plays roles in epithelial cell migration and endothelial barrier stability. Dysregulation of DOCK9 is linked to neurological defects and cancer progression through disrupted cytoskeletal control and altered cell adhesion. Knockdown studies reveal impaired filopodia formation, cell spreading, and neuronal development.

Características del producto

category

ELISA Kits


immunogen target

Dedicator Of Cytokinesis Protein 9 (DOCK9)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

ZIZ1,ZIZIMIN1,DOCK9, KIAA1058


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOCK9


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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