Docking Protein 9 (DOCK9) Antibody

Name: Docking Protein 9 (DOCK9) Antibody
Brand: Abbexa
SKU: abx232499
Price: 364 EUR
Availability: OnlineOnly

Este producto es parte de DOCK - Dedicator of Cytokinesis

Pida mas información

935106861

info@markelab.com

Precio

364€ (100 µg)

Antibody anti-DOCK9

proveedor

Abbexa

reference

abx232499

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

DOCK9 Antibody is a Rabbit Polyclonal against DOCK9.

Background

DOCK9, also known as Zizimin1, functions as a GEF for Cdc42, regulating actin remodeling, filopodia formation, and cell polarity. It is widely expressed in tissues, including the brain, where it controls neurite outgrowth, axonal guidance, and synaptic development. DOCK9 interacts with membrane phosphoinositides like PIP3 for activation, linking signaling pathways to cytoskeletal changes. It plays roles in epithelial cell migration and endothelial barrier stability. Dysregulation of DOCK9 is linked to neurological defects and cancer progression through disrupted cytoskeletal control and altered cell adhesion. Knockdown studies reveal impaired filopodia formation, cell spreading, and neuronal development.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Docking Protein 9 (DOCK9)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC, IF/ICC

purity

≥ 95% (SDS-PAGE)

purification

Purified by immunogen affinity chromatography.

recommended dilution

WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

size 1

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

DOCK9

dry ice

availability

Shipped within 5-12 working days.

alias

ZIZ1,ZIZIMIN1,DOCK9, KIAA1058

uniprot id

https://www.uniprot.org/uniprotkb/Q9BZ29

gene id

https://www.ncbi.nlm.nih.gov/gene/23348

note

Concentration: 2 mg/ml - Validity: 12 months.

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anti- DOCK9 antibody

proveedor

FineTest

reference

FNab02499

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Guanine nucleotide-exchange factor(GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induce...

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