Human Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx510776
tested applications
ELISA

Description

Human Dedicator of Cytokinesis Protein 10 (DOCK10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Dedicator of Cytokinesis Protein 10 (DOCK10) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Dedicator of Cytokinesis Protein 10 (DOCK10)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q96BY6
OMIM
611518
Alias
DOCK10, KIAA0694, ZIZ3,Zizimin-3,DRIP2, Nbla10300
Background
Elisa kits for DOCK10
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DOCK10 is a GEF for Rac1 and Cdc42, involved in regulating actin cytoskeletal dynamics, cell migration, and lymphocyte polarization. It is highly expressed in hematopoietic cells and epithelial tissues, promoting B-cell activation, dendritic cell migration, and immune surveillance. DOCK10 mediates filopodia and lamellipodia formation, enhancing membrane protrusion during cell migration. It is implicated in immune responses, particularly in B and T cells, where it supports polarization and chemotaxis. Dysregulation is associated with immune dysfunction and cancer metastasis through enhanced cell motility. Knockout models show defects in lymphocyte migration and immune cell activation.

Related Products

abx132862

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody is a Rabbit Polyclonal antibody for the detection of Dedicator of Cytokinesis Protein 10 (DOCK10).

Ver Producto
abx145342

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

DOCK10 Antibody is a Rabbit Polyclonal against DOCK10.

Ver Producto
abx301562

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

DOCK10 Antibody is a Rabbit Polyclonal against DOCK10.

Ver Producto