Human DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit
715€ (96 tests)
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935106861
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name
Human DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx509777
tested applications
ELISA
Description
Human DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 7 (DCAF7) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 7 (DCAF7) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P61962 |
| Gene ID | 10238 |
| OMIM | 605973 |
| Alias | AN11,HAN11,WDR68,SWAN-1,WD repeat-containing protein An11 homolog,WD repeat-containing protein 68 |
| Background | Elisa kits for DCAF7 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 7 (DCAF7), also known as WDR68, functions as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex and plays a critical role in protein ubiquitination and degradation. DCAF7 contains WD40 repeats, which facilitate specific protein-protein interactions, allowing the recognition and recruitment of substrates to the E3 ligase complex. It is particularly notable for its involvement in developmental signaling pathways, such as the JNK and Wnt pathways, where it regulates the stability of key transcription factors and signaling molecules. DCAF7 has also been implicated in craniofacial development and neural crest cell differentiation, with studies showing its interactions with kinases such as DYRK1A, which is crucial for neuronal development. Its dysregulation has been associated with developmental abnormalities, underscoring its importance in cellular signaling and tissue formation. Further research is needed to fully elucidate its substrate spectrum and broader biological roles.
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